The active ingredient in Ro-accutane is Isotretinoin. There are three drugs available in South Africa that contain Isotretinoin: Ro-accutane, Oratane and Acnetane. These drugs are equally effective and it does not matter which one are prescribed.
The active ingredient in Ro-accutane, Isotretinoin, is derived from Vitamin A. Many years ago, before Isotretinoin was discovered, dermatologists used high doses of Vitamin A to treat severe Acne. These high doses of Vitamin caused severe side-effects.
The side effects caused by Ro-accutane is much less severe than high doses Vitamin A. If patients are given the correct advise, before starting Ro-accutane, the side-effects are normally easy to control.
Ro-accutane has received a lot of bad press regarding the side-effects, but this has been completely blown out of proportion in the media. Ro-accutane, when used correctly, is the most effective drug to treat Acne and should be seriously considered in cases of severe Acne, scarring Acne and Acne that is not responding to other treatment option.



hello dr,
i am 26 yrs old, have irregular period since i was 12,my Gynecologist said i have hormonal problem then at first she prescribed me a
primolut and it was successfully done my 3 months session of primolut but by after 4 months without taking primolut my period again irregular so i decided to stop. by january 2011 i went to my dermatologist for my severe acne my doctor prescribed me a tretin 10mg 1tablet/day for 6months, i was so blessed my face was so amazing and free of acne and my weight was the same 52kgs. when i reached by septmber 2011 an again i went to my gynecologist for my irregular period then she prescribed me again a primolut but by november 2011 my pimples start coming severe i was so depressed. January 2012 again my dermatologist prescribed me an oratane 20mg 1capsule/day for 6 months and now i am in my 5th month and showing the good effect of the medicine.but sadly telling you that since im taking oratane 20mg i never had period and i gained weight before im just 52kgs(tretin 10mg),recently im 57kgs(oratane 20mg). i keep doing exercise and diet but no changes at all.please advise me if it is normal to gain weight with oratane 20mg,if i stop after 6th month session of my oratane would my weight back to normal or not??and for how long its gonna take to get back my normal weight?
Thanks alot.god bless
Dear Green Apple. Oratane does not influence weight. The oral contraceptive, which I presume you are taking, because you are on Oratane, can influence weight.